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Publications which have used MHMF resources

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Last Updated: 06/29/2014 03:33:30 PM

Go to Publications for year (number)  2002 (2:1) | 2003 (5:3) | 2004 (8:4) | 2005 (35:12) | 2006 (33:7) | 2007 (19:8) | 2008 (23:6) | 2009 (19:7) | 2010 (21:7) | 2011 (20:7) | 2012 (34:9) | 2013 (31:6) | 2014 (10:1)  |  NIH Access procedure

2014 Publications

Jason B Cook, Stephanie M Nelli, Mackenzie R Neighbors, Danielle H Morrow, Todd K O’Buckley, Antoniette M Maldonado-Devincci1 and A Leslie Morrow
Ethanol Alters Local Cellular Levels of (3a,5a)-3-Hydroxypregnan-20-one (3a,5a-THP) Independent of the Adrenals in Subcortical Brain Regions.
Neuropsychopharmacology (2014) 39, 1978–1987

Jason B. Cook, David F. Werner, Antoniette M. Maldonado-Devincci, Maggie N. Leonard, Kristen R. Fisher, Todd K. O’Buckley, Patrizia Porcu, Thomas J. McCown, Joyce Besheer, Clyde W. Hodge, and A. Leslie Morrow
Overexpression of the Steroidogenic Enzyme Cytochrome P450 Side Chain Cleavage in the Ventral Tegmental Area
Increases 3 ,5 -THP and Reduces Long-Term Operant Ethanol Self-Administration
The Journal of Neuroscience, April 23, 2014 34(17):5824–5834

Carver K, Ming X, Juliano RL
Multicellular tumor spheroids as a model for assessing delivery of oligonucleotides in three dimensions.
2014 Mar 11;3:e153. doi: 10.1038/mtna.2014.5

Ostrowski LE, Yin W, Patel M, Sechelski J, Rogers T, Burns K, Grubb BR, Olsen JC
Restoring ciliary function to differentiated primary ciliary dyskinesia cells with a lentiviral vector.
2014 Mar;21(3):253-61. doi: 10.1038/gt.2013.79. Epub 2014 Jan 23.

Zou JY, Crews FT.
Release of Neuronal HMGB1 by Ethanol through Decreased HDAC Activity Activates Brain Neuroimmune Signaling.
2014 Feb 14;9(2):e87915. doi: 10.1371/journal.pone.0087915. eCollection 2014

Choudhury R, Roy SG, Tsai YS, Tripathy A, Graves LM, Wang Z
The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.
2014 Jan 23;5:3078. doi: 10.1038/ncomms4078

Wadosky KM, Rodriguez JE, Hite RL, Min JN, Walton B, Willis MS.
Muscle RING Finger-1 Attenuates IGF-1-dependent cardiomyocyte hypertrophy by Inhibiting JNK Signaling.
2014 Jan 14. [Epub ahead of print

Annayev Y, Adar S, Chiou YY, Lieb J, Sancar A, Ye R
Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor that Modulates Circadian Gene Expression.
2014 Jan 2. [Epub ahead of print]

Lu Y1, Slomberg DL1, Schoenfisch MH2
Nitric oxide-releasing chitosan oligosaccharides as antibacterial agents
2014 Feb;35(5):1716-24. doi: 10.1016/j.biomaterials.2013.11.015. Epub 2013 Nov 20.

Nakagawa O, Ming X, Carver K, Juliano R
Conjugation with Receptor-Targeted Histidine-Rich Peptides Enhances the Pharmacological Effectiveness of Antisense Oligonucleotides.
Bioconjugate Chem., 2014, 25 (1), pp 165–170.

2013 Publications

Kanther M1, Tomkovich S, Xiaolun S, Grosser MR, Koo J, Flynn EJ 3rd, Jobin C, Rawls JF.
Commensal microbiota stimulate systemic neutrophil migration through induction of Serum amyloid A.
2013 Dec 26. doi: 10.1111/cmi.12257. [Epub ahead of print

Burette AC1, Park H, Weinberg RJ
Postsynaptic distribution of IRSp53 in spiny excitatory and inhibitory neurons.
2013 Dec 17. doi: 10.1002/cne.23526. [Epub ahead of print

McCall NM1, Sprow GM2, Delpire E3, Thiele TE2, Kash TL1, Pleil KE1
Effects of sex and deletion of neuropeptide Y2 receptors from GABAergic neurons on affective and alcohol drinking behaviors in mice.
2013 Dec 25;7:100. doi: 10.3389/fnint.2013.00100

Michelle G. Roy, Alessandra Livraghi-Butrico, Ashley A. Fletcher, Melissa M. McElwee, Scott E. Evans, Ryan M. Boerner, Samantha N. Alexander, Lindsey K. Bellinghausen, Alfred S. Song, Youlia M. Petrova, Michael J. Tuvim, Roberto Adachi, Irlanda Romo, Andrea S. Bordt, M. Gabriela Bowden, Joseph H. Sisson, Prescott G. Woodruff, David J. Thornton, Karine Rousseau, Maria M. De la Garza, Seyed J. Moghaddam, Harry Karmouty-Quintana, Michael R. Blackburn, Scott M. Drouin, C. William Davis, Kristy A. Terrell, Barbara R. Grubb, Wanda K. O’Neal, Sonia C. Flores, Adela Cota-Gomez, Catherine A. Lozupone, Jody M. Donnelly, Alan M. Watson, Corinne E. Hennessy, Rebecca C. Keith, Ivana V. Yang, Lea Barthel, Peter M. Henson, William J. Janssen, David A. Schwartz, Richard C. Boucher, Burton F. Dickey & Christopher M. Evans
Muc5b is required for airway defence.
Nature 2013           doi:10.1038/nature12807

Beltran1 AS, Graves1 LM and Blancafort P
Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function
Oncogene 2013, 1–11. doi: 10.1038/onc.2013.422. [Epub ahead of print]

Bove PF, Dang H, Cheluvaraju C, Jones LC, Liu X, O'Neal WK, Randell SH, Schlegel R, Boucher RC
Breaking the In-Vitro Alveolar Type II Cell Proliferation Barrier While Retaining Ion Transport Properties.
2013 Nov 5. [Epub ahead of print]

Gessner RC, Hanson AD, Feingold S, Cashion AT, Corcimaru A, Wu BT, Mullins CR, Aylward SR, Reid LM, Dayton PA.
Functional ultrasound imaging for assessment of extracellular matrix scaffolds used for liver organoid formation.
2013 Dec;34(37):9341-51. doi: 10.1016/j.biomaterials.2013.08.033. Epub 2013 Sep 4

Varma D, Wan X, Cheerambathur D, Gassmann R, Suzuki A, Lawrimore J, Desai A, Salmon ED.
Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores.
2013 Sep 2;202(5):735-46. doi: 10.1083/jcb.201304197. Epub 2013 Aug 26

Slomberg DL, Lu Y, Broadnax AD, Hunter RA, Carpenter AW, Schoenfisch MH
Role of Size and Shape on Biofilm Eradication for Nitric Oxide-Releasing Silica Nanoparticles.
2013 Sep 5. [Epub ahead of print]

Lu Y, Slomberg DL, Shah A, Schoenfisch MH.
Nitric Oxide-Releasing Amphiphilic Poly(amidoamine) (PAMAM) Dendrimers as Antibacterial Agents
2013 Sep 6. [Epub ahead of print]

Ozkan-Dagliyan I, Chiou YY, Ye R, Hassan BH, Ozturk N, Sancar A
Formation of Arabidopsis Cryptochrome 2 Photobodies in Mammalian Nuclei: APPLICATION AS AN OPTOGENETIC DNA DAMAGE CHECKPOINT SWITCH.
2013 Aug 9;288(32):23244-51. doi: 10.1074/jbc.M113.493361. Epub 2013 Jul 5.

Ngok SP, Geyer R, Kourtidis A, Mitin N, Feathers R, Der C, Anastasiadis PZ
TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function
2013 Aug 1;126(Pt 15):3271-7. doi: 10.1242/jcs.123869. Epub 2013 May 31

Wang Y, Lanzoni G, Carpino G, Cui CB, Dominguez-Bendala J, Wauthier E, Cardinale V, Oikawa T, Pileggi A, Gerber D, Furth ME, Alvaro D, Gaudio E, Inverardi L, Reid LM
Biliary Tree Stem Cells, Precursors to Pancreatic Committed Progenitors: Evidence for Possible Life-Long Pancreatic Organogenesis.
2013 Jul 11. doi: 10.1002/stem.1460. [Epub ahead of print

Mitin N, Rossman KL, Currin R, Anne S, Marshall TW, Bear JE, Bautch VL, Der CJ
The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility
2013 Jun 18;8(6):e66260. Print 2013

Li Y, Masaki T, Lemon SM.
miR-122 and the Hepatitis C RNA genome: More than just stability.
2013 Jun 1;10(6):919-24. doi: 10.4161/rna.25137. Epub 2013 May 22

Vetreno RP, Qin L, Crews FT
Increased receptor for advanced glycation end product expression in the human alcoholic prefrontal cortex is linked to adolescent drinking.
2013 Jul 15;59C:52-62. doi: 10.1016/j.nbd.2013.07.002. [Epub ahead of print

Qin L, Liu Y, Hong JS, Crews FT
NADPH oxidase and aging drive microglial activation, oxidative stress, and dopaminergic neurodegeneration following systemic LPS administration.
2013 Jun;61(6):855-68. doi: 10.1002/glia.22479. Epub 2013 Mar 28

Tomonori Nochi, Paul W. Denton, Angela Wahl, and J. Victor Garcia
Cryptopatches Are Essential for the Development of Human GALT
Cell Reports 20 June 2013

Martino MB, Jones L, Brighton B, Ehre C, Abdulah L, Davis CW, Ron D, O'Neal WK, Ribeiro CM.
The ER stress transducer IRE1β is required for airway epithelial mucin production.
2013 May;6(3):639-54. doi: 10.1038/mi.2012.105. Epub 2012 Nov 21

Dansako H, Yamane D, Welsch C, McGivern DR, Hu F, Kato N, Lemon SM.
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells.
2013 May;9(5):e1003345. doi: 10.1371/journal.ppat.1003345. Epub 2013 May 23

Li C, McCall NM, Lopez AJ, Kash TL
Alcohol effects on synaptic transmission in periaqueductal gray dopamine neurons.
2013 Apr 15. pii: S0741-8329(13)00040-2. doi: 10.1016/j.alcohol.2013.02.002. [Epub ahead of print]

Ming X, Carver K, Fisher M, Noel R, Cintrat JC, Gillet D, Barbier J, Cao C, Bauman J, Juliano RL
The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides
2013 Apr 1;41(6):3673-87. doi: 10.1093/nar/gkt066. Epub 2013 Feb 8.

Ahir BK, Sanders AP, Rager JE, Fry RC
Systems biology and birth defects prevention: blockade of the glucocorticoid receptor prevents arsenic-induced birth defects.
2013 Mar;121(3):332-8. doi: 10.1289/ehp.1205659. Epub 2012 Dec 21

Feng Z, Hensley L, McKnight KL, Hu F, Madden V, Ping L, Jeong SH, Walker C, Lanford RE, Lemon SM
A pathogenic picornavirus acquires an envelope by hijacking cellular membranes.
2013 Mar 31. doi: 10.1038/nature12029. [Epub ahead of print]

Duan J, Lee Y, Jania C, Gong J, Rojas M, Burk L, Willis M, Homeister J, Tilley S, Rubin J, Deb A.
Rib fractures and death from deletion of osteoblast βcatenin in adult mice is rescued by corticosteroids.
2013;8(2):e55757. doi: 10.1371/journal.pone.0055757. Epub 2013 Feb 5

Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR
Loss of Cftr function exacerbates the phenotype of Na+ hyperabsorption in murine airways.
2013 Feb 1. [Epub ahead of print]

Sesma JI, Kreda SM, Okada SF, van Heusden C, Moussa L, Jones LC, O'Neal WK, Togawa N, Hiasa M, Moriyama Y, Lazarowski ER
The vesicular nucleotide transporter (VNUT) regulates the nucleotide content in airway epithelial mucin granules.
Am J Physiol Cell Physiol. 2013 Mar 6. [Epub ahead of print]

Sears PR1, Thompson K, Knowles MR, Davis CW
Human airway ciliary dynamics.
2013 Feb 1;304(3):L170-83. doi: 10.1152/ajplung.00105.2012. Epub 2012 Nov 9

Turner RA, Wauthier E, Lozoya O, McClelland R, Bowsher JE, Barbier C, Prestwich G, Hsu E, Gerber DA, Reid LM
Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts.
2013 Feb;57(2):775-84. doi: 10.1002/hep.26065. Epub 2013 Jan 10

Cocchiaro JL1, Rawls JF
Microgavage of zebrafish larvae.
2013 Feb 20;(72):e4434. doi: 10.3791/4434.

Kapustina M, Elston TC, Jacobson K.
Compression and dilation of the membrane-cortex layer generates rapid changes in cell shape.
J Cell Biol. 2013 Jan 7;200(1):95-108. doi: 10.1083/jcb.201204157.

2012 Publications

Suprynowicz FA, Upadhyay G, Krawczyk E, Kramer SC, Hebert JD, Liu X, Yuan H, Cheluvaraju C, Clapp PW, Boucher RC Jr, Kamonjoh CM, Randell SH, Schlegel R
Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells
2012 Dec 4;109(49):20035-40.

Copyright PNAS 2013

Li Y, Masaki T, Yamane D, McGivern DR, Lemon SM.
Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication.
2012 Dec 17. [Epub ahead of print]

Crews FT, Qin L, Sheedy D, Vetreno RP, Zou J
High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence.
2012 Nov 30. pii: S0006-3223(12)00889-X. doi: 10.1016/j.biopsych.2012.09.030. [Epub ahead of print]

Martino MB, Jones L, Brighton B, Ehre C, Abdulah L, Davis CW, Ron D, O'Neal WK, Ribeiro CM.
The ER stress transducer IRE1β is required for airway epithelial mucin production.
2012 Nov 21. doi: 10.1038/mi.2012.105. [Epub ahead of print]

Rothbart SB, Krajewski K, Nady N, Tempel W, Xue S, Badeaux AI, Barsyte-Lovejoy D, Martinez JY, Bedford MT, Fuchs SM, Arrowsmith CH, Strahl BD
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation.
2012 Nov;19(11):1155-60. doi: 10.1038/nsmb.2391. Epub 2012 Sep 30

Choudhury R, Tsai YS, Dominguez D, Wang Y, Wang Z.
Engineering RNA endonucleases with customized sequence specificities.
2012;3:1147. doi: 10.1038/ncomms2154

Hassiotou F, Beltran A, Chetwynd E, Stuebe AM, Twigger AJ, Metzger P, Trengove N, Lai CT, Filgueira L, Blancafort P, Hartmann PE.
Breastmilk is a novel source of stem cells with multilineage differentiation potential.
2012 Oct;30(10):2164-74. doi: 10.1002/stem.1188

Bohórquez EB, Chua M, Meshnick SR.
Quinine localizes to a non-acidic compartment within the food vacuole of the malaria parasite Plasmodium falciparum.
2012 Oct 22;11(1):350. [Epub ahead of print

Vetreno RP, Crews FT
Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and toll-like receptors in the adult prefrontal cortex.
2012 Dec 13;226:475-88. doi: 10.1016/j.neuroscience.2012.08.046. Epub 2012 Sep 15

Ostrowski LE, Stewart D, Hazucha M.
Interferon γ stimulates accumulation of gas phase nitric oxide in differentiated cultures of normal and cystic fibrosis airway epithelial cells.
2012 Oct;190(5):563-71. Epub 2012 Jun 23.

Sun B, Slomberg DL, Chudasama SL, Lu Y, Schoenfisch MH.
Nitric oxide-releasing dendrimers as antibacterial agents.
2012 Oct 8;13(10):3343-54. doi: 10.1021/bm301109c. Epub 2012 Sep 26

Carpenter AW, Worley BV, Slomberg DL, Schoenfisch MH
Dual action antimicrobials: nitric oxide release from quaternary ammonium-functionalized silica nanoparticles.
2012 Oct 8;13(10):3334-42. doi: 10.1021/bm301108x. Epub 2012 Sep 21

Ehre C, Worthington EN, Liesman RM, Grubb BR, Barbier D, O'Neal WK, Sallenave JM, Pickles RJ, Boucher RC.
Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs.
2012 Oct 9;109(41):16528-33. doi: 10.1073/pnas.1206552109. Epub 2012 Sep 24

Hoopes SL, Willcockson HH, Caron KM
Characteristics of multi-organ lymphangiectasia resulting from temporal deletion of calcitonin receptor-like receptor in adult mice
2012;7(9):e45261. doi: 10.1371/journal.pone.0045261. Epub 2012 Sep 17

Kesimer M, Ehre C, Burns KA, Davis CW, Sheehan JK, Pickles RJ.
Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways.
2012 Aug 29. doi: 10.1038/mi.2012.81. [Epub ahead of print]

Mitin N, Rossman KL, Der CJ
Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4
2012;7(7):e41876. doi: 10.1371/journal.pone.0041876. Epub 2012 Jul 24.

Yu D, Thelin WR, Randell SH, Boucher RC
Expression profiles of aquaporins in rat conjunctiva, cornea, lacrimal gland and Meibomian gland
2012 Jul 22. [Epub ahead of print]

Yu D, Thelin WR, Rogers TD, Stutts MJ, Randell SH, Grubb BR, Boucher RC.
Regional Differences in Rat Conjunctival Ion Transport Activities.
2012 Jul 18. [Epub ahead of print

Kim SK, Foote MB, Huang L.
Targeted delivery of EV peptide to tumor cell cytoplasm using lipid coated calcium carbonate nanoparticles.
2012 Jul 14. [Epub ahead of print

Qin L, Crews FT.
Chronic ethanol increases systemic TLR3 agonist-induced neuroinflammation and neurodegeneration.
2012 Jun 18;9(1):130. [Epub ahead of print]

Henderson MW1, Inatsuka CS, Sheets AJ, Williams CL, Benaron DJ, Donato GM, Gray MC, Hewlett EL, Cotter PA
Contribution of Bordetella filamentous hemagglutinin and adenylate cyclase toxin to suppression and evasion of interleukin-17-mediated inflammation.
2012 Jun;80(6):2061-75. doi: 10.1128/IAI.00148-12. Epub 2012 Apr 2.

Human Breast Milk and Antiretrovirals Dramatically Reduce Oral HIV-1 Transmission in BLT Humanized Mice
Wahl A, Swanson MD, Nochi T, Olesen R, Denton PW, Chateau M, Garcia JV.
PLoS Pathog. 2012 Jun;8(6):e1002732. Epub 2012 Jun 14.

Zou J, Crews FT
Inflammasome-IL-1β Signaling Mediates Ethanol Inhibition of Hippocampal Neurogenesis.
Front Neurosci. 2012;6:77. Epub 2012 May 30

Varma D, Chandrasekaran S, Sundin LJ, Reidy KT, Wan X, Chasse DA, Nevis KR, DeLuca JG, Salmon ED, Cook JG
Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment.
2012 May 13;14(6):593-603. doi: 10.1038/ncb2489.

Kim SK, Foote MB, Huang L
The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles.
2012 May;33(15):3959-66. Epub 2012 Feb 25.

Martin TD, Mitin N, Cox AD, Yeh JJ, Der CJ
Phosphorylation by protein kinase Cα regulates RalB small GTPase protein activation, subcellular localization, and effector utilization.
J Biol Chem. 2012 Apr 27;287(18):14827-36. Epub 2012 Mar 5

Neel NF, Rossman KL, Martin TD, Hayes TK, Yeh JJ, Der CJ
The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector.
Mol Cell Biol. 2012 Apr;32(8):1374-86. Epub 2012 Feb 13

Mitin N, Roberts PJ, Chenette EJ, Der CJ.
Posttranslational lipid modification of Rho family small GTPases
Methods Mol Biol. 2012;827:87-95.

Livraghi-Butrico A, Kelly EJ, Klem ER, Dang H, Wolfgang MC, Boucher RC, Randell SH, O'Neal WK
Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation.
Mucosal Immunol. 2012 Mar 14. doi: 10.1038/mi.2012.17. [Epub ahead of print

Livraghi-Butrico A, Grubb BR, Kelly EJ, Wilkinson KJ, Yang H, Geiser M, Randell SH, Boucher RC, O'Neal WK.
Genetically Determined Heterogeneity of Lung Disease in a Mouse Model of Airway Mucus Obstruction.
Physiol Genomics. 2012 Mar 6. [Epub ahead of print

Jones LC, Moussa L, Fulcher ML, Zhu Y, Hudson EJ, O'Neal WK, Randell SH, Lazarowski ER, Boucher RC, Kreda SM.
VAMP8 is a vesicle SNARE that regulates mucin secretion in airway goblet cells.
J Physiol. 2012 Feb 1;590(Pt 3):545-62. Epub 2011 Dec 5.

ATP-P2X7 receptor signaling controls basal and TNFα-stimulated glial cell proliferation (pages 661–673), Jian Zou, Ryan P. Vetreno and Fulton T. Crews, Published online: 1 FEB 2012 | DOI: 10.1002/glia.22302

© 2012 Wiley Periodicals Inc. "Confocal analysis was performed using a LeicaSP2 AOBS Upright Laser Scanning Confocal in the Michael Hooker Microscopy Facility at UNC."


Qin L, Crews FT
NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration.
J Neuroinflammation. 2012 Jan 12;9:5. doi: 10.1186/1742-2094-9-5.

Denton PW, Olesen R, Choudhary SK, Archin NM, Wahl A, Swanson MD, Chateau M, Nochi T, Krisko JF, Spagnuolo RA, Margolis DM, Garcia JV.
Generation of HIV latency in humanized BLT mice.
J Virol. 2012 Jan;86(1):630-4. Epub 2011 Oct 19


2011 Publications

Wiley DM, Jin SW
Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates
2011 Dec;22(9):1012-8. doi: 10.1016/j.semcdb.2011.10.005. Epub 2011 Oct 12.

Duan J, Gherghe C, Liu D, Hamlett E, Srikantha L, Rodgers L, Regan JN, Rojas M, Willis M, Leask A, Majesky M, Deb A.
Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair.
EMBO J. 2011 Nov 15. doi: 10.1038/emboj.2011.418. [Epub ahead of print]

Qu L, Feng Z, Yamane D, Liang Y, Lanford RE, Li K, Lemon SM.
Disruption of TLR3 signaling due to cleavage of TRIF by the hepatitis A virus protease-polymerase processing intermediate, 3CD.
PLoS Pathog. 2011 Sep;7(9):e1002169. Epub 2011 Sep 8

Carpenter AW, Slomberg DL, Rao KS, Schoenfisch MH
Influence of scaffold size on bactericidal activity of nitric oxide-releasing silica nanoparticles.
ACS Nano. 2011 Sep 27;5(9):7235-44. Epub 2011 Aug 29.

Clunes LA, Davies CM, Coakley RD, Aleksandrov AA, Henderson AG, Zeman KL, Worthington EN, Gentzsch M, Kreda SM, Cholon D, Bennett WD, Riordan JR, Boucher RC, Tarran R.
Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration.
FASEB J. 2011 Oct 11. [Epub ahead of print]

Grubb BR, O'Neal WK, Ostrowski LE, Kreda SM, Button B, Boucher RC.
Transgenic hCFTR expression fails to correct {beta}ENaC mouse lung disease.
Am J Physiol Lung Cell Mol Physiol. 2011 Oct 14. [Epub ahead of print]

McClelland R, Wauthier E, Tallheden T, Reid LM, Hsu E.
In situ labeling and magnetic resonance imaging of transplanted human hepatic stem cells.
2011 Oct;13(5):911-22. doi: 10.1007/s11307-010-0422-x

Lozoya OA, Wauthier E, Turner RA, Barbier C, Prestwich GD, Guilak F, Superfine R, Lubkin SR, Reid LM
Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche.
2011 Oct;32(30):7389-402. doi: 10.1016/j.biomaterials.2011.06.042. Epub 2011 Jul 23

Zhang L, Collins PL, Lamb RA, Pickles RJ.
Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5 (W3A), parainfluenza virus type 3, and respiratory syncytial virus.
Virology. 2011 Oct 8. [Epub ahead of print]

Li W, Zhang L, Wu Z, Pickles RJ, Samulski RJ.
AAV-6 mediated efficient transduction of mouse lower airways.
Virology. 2011 Sep 1;417(2):327-33. Epub 2011 Jul 14.

Okada SF, Zhang L, Kreda SM, Abdullah LH, Davis CW, Pickles RJ, Lazarowski ER, Boucher RC.
Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium.
Am J Respir Cell Mol Biol. 2011 Aug;45(2):253-60. Epub 2010 Oct 8.

Kim SK, Huang L.
Nanoparticle delivery of a peptide targeting EGFR signaling.
J Control Release. 2011 Aug 17. [Epub ahead of print]

Wiley DM, Kim JD, Hao J, Hong CC, Bautch VL, Jin SW.
Distinct signalling pathways regulate sprouting angiogenesis from the dorsal aorta and the axial vein.
2011 Jun;13(6):686-92. doi: 10.1038/ncb2232. Epub 2011 May 15.

Debjit Dutta, Abigail Pulsipher, Wei Luo, and Muhammad N. Yousaf
Synthetic Chemoselective Rewiring of Cell Surfaces: Generation of Three-Dimensional Tissue Structures
J Am Chem Soc. 2011 Jun 8;133(22):8704-13. Epub 2011 May 11

Weinberg, M.S., Blake, B.L., Samulski, R.J. & McCown, T.J.
The influence of epileptic neuropathology and prior peripheral immunity on CNS transduction by rAAV2 and rAAV5.
Gene Ther (2011).doi:10.1038/gt.2011.49

Johnson JS, Gentzsch M, Zhang L, Ribeiro CM, Kantor B, Kafri T, Pickles RJ, Samulski RJ.
AAV exploits subcellular stress associated with inflammation, endoplasmic reticulum expansion, and misfolded proteins in models of cystic fibrosis.
PLoS Pathog. 2011 May;7(5):e1002053. Epub 2011 May 19.

Sears PR, Davis CW, Chua M, Sheehan JK.
Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures.
Am J Physiol Lung Cell Mol Physiol. 2011 Apr 29.

Silvia M. Kreda and Martina Gentzsch
Imaging CFTR Protein Localization in Cultured Cells and Tissues, M.D. Amaral, K. Kunzelmann (eds.)
Chapter 2, p15-33, Cystic Fibrosis, Methods in Molecular Biology 742, DOI 10.1007/978-1-61779-120-8_2
, Springer Science+Business Media

Zand TP, Reiner DJ, Der CJ.
Ras effector switching promotes divergent cell fates in C. elegans vulval patterning
Dev Cell. 2011 Jan 18;20(1):84-96.

Gherghe CM, Duan J, Gong J, Rojas M, Klauber-Demore N, Majesky M, Deb A.
Wnt1 is a proangiogenic molecule, enhances human endothelial progenitor function, and increases blood flow to ischemic limbs in a HGF-dependent manner.
FASEB J. 2011 Feb 14. [Epub ahead of print]

2010 Publications

Zucker RM, Chua M.
Evaluation and purchase of confocal microscopes: numerous factors to consider. Curr Protoc Cytom. 2010 Oct;Chapter 2:Unit2.16.

Okada SF, Zhang L, Kreda SM, Abdullah LH, Davis CW, Pickles RJ, Lazarowski ER, Boucher RC
Coupled Nucleotide and Mucin Hypersecretion from Goblet Cell Metaplastic Human Airway Epithelium.

Am J Respir Cell Mol Biol
. 2010 Oct 8. Epub ahead of print

Mall MA, Button B, Johannesson B, Zhou Z, Livraghi A, Caldwell RA, Schubert SC, Schultz C, O'Neal WK, Pradervand S, Hummler E, Rossier BC, Grubb BR, Boucher RC.
Airway surface liquid volume regulation determines different airway phenotypes in liddle compared with betaENaC-overexpressing mice.
J Biol Chem. 2010 Aug 27;285(35):26945-55. Epub 2010 Jun 21.

Kreda SM, Seminario-Vidal L, van Heusden CA, O'Neal W, Jones L, Boucher RC, Lazarowski ER.
Receptor-promoted exocytosis of airway epithelial mucin granules containing a spectrum of adenine nucleotides.
J Physiol. 2010 Jun 15;588(Pt 12):2255-67. Epub 2010 Apr 26

Bove PF, Grubb BR, Okada SF, Ribeiro CM, Rogers TD, Randell SH, O'Neal WK, Boucher RC.
Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling.
J Biol Chem. 2010 Nov 5;285(45):34939-49. Epub 2010 Aug 27.

Cholon DM, O'Neal WK, Randell SH, Riordan JR, Gentzsch M.
Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures
Am J Physiol Lung Cell Mol Physiol. 2010 Mar;298(3):L304-14. Epub 2009 Dec 11

Ostrowski LE, Yin W, Rogers TD, Busalacchi KB, Chua M, O'Neal WK, Grubb BR
Conditional deletion of dnaic1 in a murine model of primary ciliary dyskinesia causes chronic rhinosinusitis
Am J Respir Cell Mol Biol. 2010 Jul;43(1):55-63. Epub 2009 Aug 12

Vigil D, Martin TD, Williams F, Yeh JJ, Campbell SL, Der CJ
Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms.
J Biol Chem. 2010 Nov 5;285(45):34729-40. Epub 2010 Aug 27

Shobhan Gaddameedhi, Michael G. Kemp, Joyce T. Reardon, Janiel M. Shields, Stephanie L. Smith-Roe, William K. Kaufmann, Aziz Sancar
Similar nucleotide excision repair capacity in melanocytes and melanoma cells
Cancer Res. Author manuscript; available in PMC 2011 June 15.

Stevens EV, Carpenter AW, Shin JH, Liu J, Der CJ, Schoenfisch MH
Nitric oxide-releasing silica nanoparticle inhibition of ovarian cancer cell growth.
Mol Pharm. 2010 Jun 7;7(3):775-85

Hanker AB, Mitin N, Wilder RS, Henske EP, Tamanoi F, Cox AD, Der CJ.
Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.

Oncogene. 2010 Jan 21;29(3):380-91. Epub 2009 Oct 19.

Chen Y, Bathula SR, Li J, Huang L
Multifunctional nanoparticles delivering small interfering RNA and doxorubicin overcome drug resistance in cancer.
J Biol Chem
. 2010 Jul 16;285(29):22639-50. Epub 2010 May 11

Jolly PS, Berkowitz P, Bektas M, Lee HE, Chua M, Diaz LA, Rubenstein DS.
p38MAPK signaling and desmoglein-3 internalization are linked events in pemphigus acantholysis.
J Biol Chem. 2010 Mar 19;285(12):8936-41. Epub 2010 Jan 21.

Gray SJ, Blake BL, Criswell HE, Nicolson SC, Samulski RJ, McCown TJ, Li W
Directed evolution of a novel adeno-associated virus (AAV) vector that crosses the seizure-compromised blood-brain barrier (BBB).
Mol Ther. 2010 Mar;18(3):570-8. Epub 2009 Dec 29. Erratum in: Mol Ther. 2010 May;18(5):1054. Li, Wuping [added]

Johnson JS, Li C, DiPrimio N, Weinberg MS, McCown TJ, Samulski RJ.
Mutagenesis of adeno-associated virus type 2 capsid protein VP1 uncovers new roles for basic amino acids in trafficking and cell-specific transduction.
J Virol. 2010 Sep;84(17):8888-902. Epub 2010 Jun 23.

Budd SJ, Hartnett ME
Increased angiogenic factors associated with peripheral avascular retina and intravitreous neovascularization: a model of retinopathy of prematurity.
Arch Ophthalmol. 2010 May;128(5):589-95.

Loechner KJ, Salmon WC, Fu J, Patel S, McLaughlin JT
Cell Cycle-Dependent Localization of Voltage-Dependent Calcium Channels and the Mitotic Apparatus in a Neuroendocrine Cell Line(AtT-20).
Int J Cell Biol. 2009;2009:487959. Epub 2010 Jan 6.

Zou J, Crews F
Induction of innate immune gene expression cascades in brain slice cultures by ethanol: key role of NF-κB and proinflammatory cytokines.
Alcohol Clin Exp Res. 2010 May;34(5):777-89. Epub 2010 Mar 3

Aleksandrov AA, Kota P, Aleksandrov LA, He L, Jensen T, Cui L, Gentzsch M, Dokholyan NV, Riordan JR
Regulatory insertion removal restores maturation, stability and function of DeltaF508 CFTR
J Mol Biol. 2010 Aug 13;401(2):194-210. Epub 2010 Jun 16

Kenyon KA, Bushong EA, Mauer AS, Strehler EE, Weinberg RJ, Burette AC
Cellular and subcellular localization of the neuron-specific plasma membrane calcium ATPase PMCA1a in the rat brain.
J Comp Neurol. 2010 Aug 15;518(16):3169-83

Burette AC, Strehler EE, Weinberg RJ
A plasma membrane Ca2+ ATPase isoform at the postsynaptic density.
Neuroscience. 2010 Sep 1;169(3):987-93. Epub 2010 Jun 3
(cover photo)


2009 Publications

Budd S, Byfield G, Martiniuk D, Geisen P, Hartnett ME
Reduction in endothelial tip cell filopodia corresponds to reduced intravitreous but not intraretinal vascularization in a model of ROP.
Exp Eye Res. 2009 Nov;89(5):718-27. Epub 2009 Jul 1.

M. Casiraghi, J. Tatreau, J. Abano, J. Blackwell, L. Watson, K. Burridge, S. Randell, T. Egan
In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation
J Thorac Cardiovasc Surg. 2009 Sep;138(3):760-7

Cholon DM, O'Neal WK, Randell SH, Riordan JR, Gentzsch M.
Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures.
Am J Physiol Lung Cell Mol Physiol. 2010 Mar;298(3):L304-14. Epub 2009 Dec 11

Ostrowski LE, Yin W, Rogers TD, Busalacchi KB, Chua M, O'Neal WK, Grubb BR.
Conditional Deletion of Dnaic1 in a Murine Model of Primary Ciliary Dyskinesia Causes Chronic Rhinosinusitis.
Am J Respir Cell Mol Biol. 2009 Aug 12. [Epub ahead of print]

Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ.
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium.
PLoS Biol. 2009 Jul;7(7):e1000155. Epub 2009 Jul 21.

Kalantry S, Purushothaman S, Bowen RB, Starmer J, Magnuson T.
Evidence of Xist RNA-independent initiation of mouse imprinted X-chromosome inactivation.
Nature. 2009 Jul 1. [Epub ahead of print]

Ribeiro CM, Hurd H, Wu Y, Martino ME, Jones L, Brighton B, Boucher RC, O'Neal WK.
Azithromycin treatment alters gene expression in inflammatory, lipid metabolism, and cell cycle pathways in well-differentiated human airway epithelia.
PLoS One. 2009 Jun 5;4(6):e5806

Tuvim MJ, Mospan AR, Burns KA, Chua M, Mohler PJ, Melicoff E, Adachi R, Ammar-Aouchiche Z, Davis CW, Dickey BF.
Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.
J Biol Chem. 2009 Apr 10;284(15):9781-7. Epub 2009 Feb 10.

Lee HE, Berkowitz P, Jolly PS, Diaz LA, Chua MP, Rubenstein DS., Biphasic activation of p38MAPK suggests that apoptosis is a downstream event in pemphigus acantholysis,
May 1;284(18):12524-32. Epub 2009 Mar 7.

Slade KM, Baker M, Chua M, Thompson NL, Pielak GJ
Effects of Recombinant Protein Expression on Green Fluorescent Protein Diffusion in Escherichia coli
Biochemistry 2009, 48, 5083–5089 5083

Cha JY, Maddileti S, Mitin N, Harden TK, Der CJ.
Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform.
J Biol Chem. 2009 Mar 6;284(10):6227-40. Epub 2008 Dec 22.

Livraghi A, Grubb BR, Hudson EJ, Wilkinson KJ, Sheehan JK, Mall MA, O'Neal WK, Boucher RC, Randell SH.
Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment.
J Immunol. 2009 Apr 1;182(7):4357-67.

Martino ME, Olsen JC, Fulcher NB, Wolfgang MC, O'Neal WK, Ribeiro CM.
Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca2+ Store Expansion Is Mediated by X-box Binding Protein-1.
J Biol Chem. 2009 May 29;284(22):14904-13. Epub 2009 Mar 25.

About the Cover

Cover FigureOn The Cover: Airway epithelial inflammation triggered by luminal exposure to Pseudomonas aeruginosa induces endoplasmic reticulum expansion, as visualized by calreticulin stain (green). Nuclei are stained with DAPI (4`,6-diamidino-2-phenylindole) (blue). The endoplasmic reticulum expansion results from activation of the unfolded protein response mediated by X-box binding protein-1. For details see the article by Martino et al., pages 14904–14913.



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About the Cover

Cover Figure


Cover photograph (Copyright © 2009, American Society for Microbiology. All Rights Reserved.): Accumulation of recombinant adeno-associated virus (rAAV) particles in the nucleolus during infection. HeLa cells were infected with rAAV2 for 18 h and analyzed by immunofluorescence to detect intact capsids (yellow). A three-dimensional confocal reconstruction of infection is shown as separate frames to display progressive gating of the nucleus (blue, left) and reveal the interior of the nucleolus (magenta, subtracted from left to right). Two frames were enlarged (bottom of image) to highlight rAAV virions which enter the nucleus intact and accumulate in the nucleolus. (Johnson J., & Samulski, R. J.

Johnson J., & Samulski, R. J.
Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus.
J Virol. 2009 Mar;83(6):2632-44. Epub 2008 Dec 24
Cowley DO, Rivera-Pérez JA, Schliekelman M, He YJ, Oliver TG, Lu L, O'Quinn R, Salmon ED, Magnuson T, Van Dyke T 
Aurora-A kinase is essential for bipolar spindle formation and early development.
Mol Cell Biol. 2009 Feb;29(4):1059-71. Epub 2008 Dec 15.
Schliekelman M, Cowley DO, O'Quinn R, Oliver TG, Lu L, Salmon ED, Van Dyke T. 
Impaired Bub1 function in vivo compromises tension-dependent checkpoint function leading to aneuploidy and tumorigenesis.
Cancer Res. 2009 Jan 1;69(1):45-54.
Limberis MP, Vandenberghe LH, Zhang L, Pickles RJ, Wilson JM.
Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. 
Mol Ther. 2009 Feb;17(2):294-301. Epub 2008 Dec 9.
Bukreyev A, Marzi A, Feldmann F, Zhang L, Yang L, Ward JM, Dorward DW, Pickles RJ, Murphy BR, Feldmann H, Collins PL. 
Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge.
Virology. 2009 Jan 20;383(2):348-61. Epub 2008 Nov 17. 

Purfield AE, Tidwell RR, Meshnick SR. Malar J.
The diamidine DB75 targets the nucleus of Plasmodium falciparum.
Malar J. 2009 May 14;8:104


2008 Publications  (Alphabetical order by first author's last name)

Anti-biofilm efficacy of nitric oxide-releasing silica nanoparticles.
Hetrick EM, Shin JH, Paul HS, Schoenfisch MH.
Biomaterials. 2009 May;30(14):2782-9. Epub 2009 Feb 23.PMID: 19233464 [PubMed - indexed for MEDLINE]F

Bactericidal efficacy of nitric oxide-releasing silica nanoparticles.
Hetrick EM, Shin JH, Stasko NA, Johnson CB, Wespe DA, Holmuhamedov E, Schoenfisch MH.
ACS Nano. 2008 Feb;2(2):235-46.

Bhati R, Patterson C, Livasy CA, Fan C, Ketelsen D, Hu Z, Reynolds E, Tanner C, Moore DT, Gabrielli F, Perou CM, Klauber-Demore N.
Molecular characterization of human breast tumor vascular cells. 
Am J Pathol
. 2008, 172, 1381-90.

Sun J, Hakobyan N, Valentino LA, Feldman BL, Samulski RJ, Monahan PE. Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX.
Blood. 2008 Dec 1;112(12):4532-41. Epub 2008 Aug 20.

Berkowitz P, Chua M, Liu Z, Diaz LA, Rubenstein DS.
Autoantibodies in the autoimmune disease pemphigus foliaceus induce blistering via p38 mitogen-activated protein kinase-dependent signaling in the skin.
Am J Pathol. 2008 Dec;173(6):1628-36

Donaldson EF, Yount B, Sims AC, Burkett S, Pickles RJ, Baric RS.
Systematic assembly of a full-length infectious clone of human coronavirus NL63.
 J Virol. 2008 Dec;82(23):11948-57. Epub 2008 Sep 25.

Davis CW, Dickey BF
Regulated airway goblet cell mucin secretion.
Annu Rev Physiol. 2008;70:487-512. Review

Chamberlain SJ, Yee D, Magnuson T 
Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency.
Stem Cells. 2008 Jun;26(6):1496-505.
Fulcher ML, Gabriel SE, Olsen JC, Tatreau JR, Gentzsch M, Livanos E, Saavedra MT, Salmon P, Randell SH 
Novel human bronchial epithelial cell lines for cystic fibrosis research.
Am J Physiol Lung Cell Mol Physiol. 2009 Jan;296(1):L82-91. Epub 2008 Oct 31.
Hartnett ME, Martiniuk D, Byfield G, Geisen P, Zeng G, Bautch VL. 
Neutralizing VEGF decreases tortuosity and alters endothelial cell division orientation in arterioles and veins in a rat model of ROP: relevance to plus disease.
Invest Ophthalmol Vis Sci. 2008 Jul;49(7):3107-14.
Kreda SM, Seminario-Vidal L, Heusden C, Lazarowski ER 
Thrombin-promoted release of UDP-glucose from human astrocytoma cells.
Br J Pharmacol. 2008 Apr;153(7):1528-37. Epub 2008 Jan 21.
Liu Y, Boukhelifa M, Tribble E, Morin-Kensicki E, Uetrecht A, Bear JE, Bankaitis VA.
The Sac1 phosphoinositide phosphatase regulates Golgi membrane morphology and mitotic spindle organization in mammals.
Mol Biol Cell. 2008 Jul;19(7):3080-96. Epub 2008 May 14.
Livraghi A, Mall M, Paradiso AM, Boucher RC, Ribeiro CM.
Modelling dysregulated Na+ absorption in airway epithelial cells with mucosal nystatin treatment.
Am J Respir Cell Mol Biol. 2008 Apr;38(4):423-34
Onesto C, Shutes A, Picard V, Schweighoffer F, Der CJ.
Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
Methods Enzymol. 2008;439:111-29.
Papadeas ST, Halloran C, McCown TJ, Breese GR, Blake BL.
Changes in apical dendritic structure correlate with sustained ERK1/2 phosphorylation in medial prefrontal cortex of a rat model of dopamine D1 receptor agonist sensitization. 
J Comp Neurol. 2008 Nov 10;511(2):271-85.
Roberts PJ, Mitin N, Keller PJ, Chenette EJ, Madigan JP, Currin RO, Cox AD, Wilson O, Kirschmeier P, Der CJ.
Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification.
J Biol Chem. 2008 Sep 12;283(37):25150-63. Epub 2008 Jul 9.
Saito Y, Uppal A, Byfield G, Budd S, Hartnett ME 
Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model.
Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1591-8.
Sun J, Hakobyan N, Valentino LA, Feldman BL, Samulski RJ, Monahan 
PE.Intraarticular factor IX protein or gene replacement protects against development of hemophilic synovitis in the absence of circulating factor IX.
Blood. 2008 Dec 1;112(12):4532-41. Epub 2008 Aug 20.
Tatur S, Kreda S, Lazarowski E, Grygorczyk R.
Calcium-dependent release of adenosine and uridine nucleotides from A549 cells.
Purinergic Signal. 2008 Jun;4(2):139-146.
Zhang L, Theise N, Chua M, Reid LM.
The stem cell niche of human livers: symmetry between development and regeneration.
Hepatology. 2008 Nov;48(5):1598-607
Zhu Y, Ehre C, Abdullah LH, Sheehan JK, Roy M, Evans CM, Dickey BF, Davis CW.
Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.
J Physiol. 2008 Apr 1;586(7):1977-92
Bartlett EJ, Hennessey M, Skiadopoulos MH, Schmidt AC, Collins PL, Murphy BR, Pickles RJ.
Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium. 
J Virol. 2008 Aug;82(16):8059-70. Epub 2008 Jun 4.
Johnson JS, Samulski RJ.
Enhancement of AAV infection by mobilizing capsids into and out of the nucleolus.
J Virol. 2008 Dec 24. [Epub ahead of print]


2007 Publications  (Alphabetical order by first author's last name)

Shutes A, Onesto C, Picard V, Leblond B, Schweighoffer F, Der CJ.
Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.J Biol Chem. 2007 Dec 7;282(49):35666-78

Livraghi A, Randell SH.
Cystic fibrosis and other respiratory diseases of impaired mucus clearance.
Toxicol Pathol
. 2007;35(1):116-29. Review.

Grubb BR, Rogers TD, Kulaga HM, Burns KA, Wonsetler RL, Reed RR, Ostrowski LE.
Olfactory epithelia exhibit progressive functional and morphological defects in CF mice.
Am J Physiol Cell Physiol
. 2007 Aug;293(2):C574-83.

Fanning AS, Little BP, Rahner C, Utepbergenov D, Walther Z, Anderson JM.
The unique-5 and -6 motifs of ZO-1 regulate tight junction strand localization and scaffolding properties.
Mol Biol Cell
. 2007 Mar;18(3):721-31.

Feng D, Marshburn D, Jen D, Weinberg RJ, Taylor RM 2nd, Burette A.
Stepping into the third dimension.
J Neurosci
. 2007 Nov 21;27(47):12757-60. Review.


Burette A, Weinberg RJ
Perisynaptic organization of plasma membrane calcium pumps in cerebellar cortex.
J Comp Neurol. 2007 Feb 20;500(6):1127-35

Feng SM, Sartor CI, Hunter D, Zhou H, Yang X, Caskey LS, Dy R, Muraoka-Cook RS, Earp HS 3rd.
The HER4 cytoplasmic domain, but not its C terminus, inhibits mammary cell proliferation.
Mol Endocrinol. 2007 Aug;21(8):1861-76.

Gentzsch, M., Choudhury, A. Chang, X.B., Pagano, R., Riordan, J.R.
Missambled mutant ΔF508 CFTR in the distal secretory pathway alters cellular lipid trafficking.
J. Cell Sci.  2007;120:447-455.

Hickey AJ, Mansour HM, Telko MJ, Xu Z, Smyth HD, Mulder T, McLean R, Langridge J, Papadopoulos D.
Physical Characterization of Component Particles included in Dry Powder Inhalers: I. Strategy Review and Static Characteristics. (Invited Paper) 
J Pharm Sci: Special Issue David Grant Dedicated Issue 2007 Jan;96: (ACCEPTED, IN PRESS)

Karrasch T, Kim JS, Muhlbauer M, Magness ST, Jobin C.
Gnotobiotic IL-10-/-;NF-κBEGFP Mice Reveal the Critical Role of TLR/NF-κB Signaling in Commensal Bacteria-Induced Colitis.
J Immunol. 2007 May 15;178(10):6522-32.

Kreda SM, Okada SF, van Heusden CA, O'neal W, Gabriel S, Abdullah L, Davis CW, Boucher RC, Lazarowski ER.
Coordinated Release of Nucleotides and Mucin from Human Airway Epithelial Calu-3 Cells.
J Physiol. 2007 Oct 1;584(Pt 1):245-59. Epub 2007 Jul 26.

Maile LA, Capps BE, Ling Y, Xi G, Clemmons DR.
Hyperglycemia alters the responsiveness of smooth muscle cells to Insulin-Like Growth Factor-I.
Endocrinology  2007

Mitin N, Betts L, Yohe ME, Der CJ, Sondek J, Rossman KL.
Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Nat Struct Mol Biol. 2007 Aug 19; [Epub ahead of print]

Juan Perez-Vilar
Mucin Granule Intraluminal Organization
Am. J. Respir. Cell Mol. Biol. February 2007 vol. 36 no. 2 183-190

Rossi AH, Salmon WC, Chua M, Davis CW.
Calcium signaling in human airway goblet cells following purinergic activation.
Am J Physiol Lung Cell Mol Physiol. 2007 Jan;292(1):L92-8. Epub 2006 Sep 1. 

Tatur, S; Kreda, SM; Lazarowski, E and Grygorczyk, R
Calcium-dependent release of adenosine and uridine nucleotides from A549 cells
 PUSI 2006;(in press)

Thelin WR, Chen Y, Gentzsch M, Kreda SM, Sallee JL, Scarlett CO, Borchers CH, Jacobson K, Stutts MJ, Milgram SL.
Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR.
J Clin Invest. 2007 Feb 1;117(2):364-374. 

Wightman RM, Heien ML, Wassum KM, Sombers LA, Aragona BJ, Khan AS, Ariansen JL, Cheer JF, Phillips PE, Carelli RM.
Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens.
Eur J Neurosci. 2007 Oct;26(7):2046-54. Epub 2007 Sep 14.

Zucker RM, Rigby P, Clements I, Salmon W, Chua M.
Reliability of confocal microscopy spectral imaging systems: Use of multispectral beads.
A.  2007 Mar;71(3):174-89.

2006 Publications  (Alphabetical order by first author's last name)

Berkowitz P, Hu P, Warren S, Liu Z, Diaz LA, Rubenstein DS.
p38MAPK inhibition prevents disease in pemphigus vulgaris mice.
Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12855-60.

Chalermskulrat W, McKinnon KP, Brickey WJ, Neuringer IP, Park RC, Sterka DG, Long BR, McNeillie P, Noelle RJ, Ting JP, Aris RM.
Combined donor specific transfusion and anti-CD154 therapy achieves airway allograft tolerance.
Thorax. 2006 Jan;61(1):61-7.

Dejima K, Randell SH, Stutts MJ, Senior BA, Boucher RC.
Potential role of abnormal ion transport in the pathogenesis of chronic sinusitis.
Arch Otolaryngol Head Neck Surg. 2006 Dec;132(12):1352-62.

Ding JD, Weinberg RJ. 
Localization of soluble guanylyl cyclase in the superficial dorsal horn. 
J Comp Neurol. 2006 Apr 20;495(6):668-78. 

Donaldson SH, Bennett W, Zeman K, Knowles MR, Tarran R, and Boucher RC. 
Mucus Clearance and Lung Function in Cystic Fibrosis with Hypertonic Saline. 
NEJM 2006; 354(3):241-250.

Donaldson SH, et al.
Studies look to sea for cystic fibrosis treatment: Inhaled saline solution works where drugs failed, doctors say
By Peggy Peck, MedPageToday Managing Editor
Thursday, January 19, 2006,

Everett RS, Vanhook MK, Barozzi N, Toth I, Johnson LG.
Specific Modulation of Airway Epithelial Tight Junctions by Apical Application of an Occludin Peptide.
Mol Pharmacol. 2006 Feb;69(2):492-500.

Fanning AS, Little BP, Rahner C, Utepbergenov D, Walther Z, Anderson JM.
The Unique-5 and -6 Motifs of ZO-1 Regulate Tight Junction Strand Localization and Scaffolding Properties.
Mol Biol Cell. 2006 Dec 20; [Epub ahead of print]

Geisen P, McColm JR, Hartnett ME.
Choroidal endothelial cells transmigrate across the retinal pigment epithelium but do not proliferate in response to soluble vascular endothelial growth factor.
Exp Eye Res. 2006 Apr;82(4):608-19.

Grubb BR, Rogers TD, Diggs PC, Boucher RC, Ostrowski LE.
Culture of murine nasal epithelia: model for cystic fibrosis.
Am J Physiol Lung Cell Mol Physiol. 2006 Feb;290(2):L270-7.

Hartnett ME, Martiniuk DJ, Saito Y, Geisen P, Peterson LJ, McColm JR.
Triamcinolone reduces neovascularization, capillary density and IGF-1 receptor phosphorylation in a model of oxygen-induced retinopathy.
Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4975-82.

Hodson CA, Ambrogi IG, Scott RO, Mohler PJ, Milgram SL.
Polarized apical sorting of guanylyl cyclase C is specified by a cytosolic signal.
Traffic. 2006 Apr;7(4):456-64.

Hu P, Berkowitz P, Madden VJ, Rubenstein DS.
Stabilization of plakoglobin and enhanced keratinocyte cell-cell adhesion by intracellular O-glycosylation.
J Biol Chem. 2006 May 5;281(18):12786-91.

Jubin Ryu, Lidong Liu, Tak Pan Wong, Dong Chuan Wu, Alain Burette, Richard Weinberg, Yu Tian Wang, Morgan Sheng
A Critical Role for Myosin IIB in Dendritic Spine Morphology and Synaptic Function.
Neuron 2006;49(2):175-182.

Kalantry S, Mills KC, Yee D, Otte AP, Panning B, Magnuson T.
The Polycomb group protein Eed protects the inactive X-chromosome from differentiation-induced reactivation.
Nat Cell Biol.  2006 Feb;8(2):195-202.

Kalantry S, Magnuson T.
The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation.
PLoS Genet. 2006 May;2(5):e66. Epub 2006 May 5.

Kim S, Burette A, Chung HS, Kwon SK, Woo J, Lee HW, Kim K, Kim H, Weinberg RJ, Kim E
NGL family PSD-95–interacting adhesion molecules regulate excitatory synapse formation
Nature Neuroscience, 2006 Oct;9(10):1294-301.

McCaskill JG, Chason KD, Neuringer IP, Ghio AJ, Funkhouser WK, Tilley SL.  
Pulmonary immune responses to Propionibacterium acnes in C57BL/6 and BALB/c mice.
Am J Respir Cell Mol Biol. 2006 Sep;35(3):347-56.

McColm JR, Geisen P, Peterson LJ, Hartnett ME.
Exogenous leukemia inhibitory factor (LIF) attenuates retinal vascularization reducing cell proliferation not apoptosis.
Exp Eye Res. 2006 Aug;83(2):438-46.

McKay T, Patel M, Pickles RJ, Johnson LG, Olsen JC.
Influenza M2 envelope protein augments avian influenza hemagglutinin pseudotyping of lentiviral vectors.
Gene Ther. 2006 Apr;13(8):715-24.

Mousley CJ, Tyeryar KR, Ryan MM, Bankaitis VA.
Sec14p-like proteins regulate phosphoinositide homoeostasis and intracellular protein and lipid trafficking in yeast.
Biochem Soc Trans. 2006 Jun;34(Pt 3):346-50. Review.

Okada SF, Nicholas RA, Kreda SM, Lazarowski ER, Boucher RC.
Physiological regulation of ATP release at the apical surface of human airway epithelia.
J Biol Chem. 2006 Aug 11;281(32):22992-3002. Epub 2006 Jun 5.

Perez-Vilar J, Mabolo R, McVaugh CT, Bertozzi CR, Boucher RC.
Mucin granule intraluminal organization in living mucous/goblet cells. Roles of protein post-translational modifications and secretion.
J Biol Chem. 2006 Feb 24;281(8):4844-55.

Phillips SE, Ile KE, Boukhelifa M, Huijbregts RP, Bankaitis VA.
Specific and Nonspecific Membrane-binding Determinants Cooperate in Targeting Phosphatidylinositol Transfer Protein beta-Isoform to the Mammalian Trans-Golgi Network.2
Mol Biol Cell. 2006 Jun;17(6):2498-512.

Purfield AM., Barrett MP, Tidwell RR, Meshnick, SR.
DB75, a novel diamidine, targets the /Plasmodium falciparum/ nucleus. 
Abstract at the annual meeting of the American Society for Tropical Medicine and Hygiene, Atlanta, GA, 2006

Qi J, Chi L, Maloney M, Yang X, Bynum D, Banes AJ.
Interleukin-1beta Increases Elasticity of Human Bioartificial Tendons.
Tissue Eng.
2006 Oct;12(10):2913-25.

Qi J, Fox AM, Alexopoulos LG, Chi L, Bynum D, Guilak F, Banes AJ.
IL-1beta decreases the elastic modulus of human tenocytes.
J Appl Physiol. 2006 Jul;101(1):189-95. Epub 2006 Apr 20.

Randell SH.
Airway Epithelial Stem Cells and the Pathophysiology of Chronic Obstructive Pulmonary Disease.
Proc Am Thoracic Soc. 2006; 3:1-8

Ribeiro CM.
The role of intracellular calcium signals in inflammatory responses of polarised cystic fibrosis human airway epithelia.
Drugs R D. 2006;7(1):17-31. Review.

Jaime A. Rivera-Pérez, Hunter Diefes, Terry Magnuson
A simple enzymatic method for parietal yolk sac removal in early postimplantation mouse embryos.
Developmental Dynamics, 2006, 236, 489-493

Tarran R, Trout L, Donaldson SH, Boucher RC.
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.
J Gen Physiol. 2006 May;127(5):591-604.

Utepbergenov DI, Fanning AS, Anderson JM.
Dimerization of the scaffolding protein ZO-1 through the second PDZ domain.
J Biol Chem. 2006 Aug 25;281(34):24671-7.

Zeng G, Taylor SM, McColm JR, Kappas NC, Kearney JB, Williams LH, Hartnett ME, Bautch VL.
The orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation.
Blood. 2006 Oct 26; [Epub ahead of print]

2005 Publications (Alphabetical order by first author's last name)

Berkowitz P, Hu P, Liu Z, Diaz LA, Enghild JJ, Chua MP, Rubenstein DS.
Desmosome signaling. Inhibition of p38MAPK prevents pemphigus vulgaris IgG-induced cytoskeleton reorganization.
J Biol Chem. 2005 Jun 24;280(25):23778-84.

van Buul JD, Anthony EC, Fernandez-Borja M, Burridge K, Hordijk PL.
Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation.
J Biol Chem. 2005 Jun 3;280(22):21129-36.

Chandrasekharan S, Foley NA, Jania L, Clark P, Audoly LP, Koller BH.
Coupling of COX-1 to mPGES1 for prostaglandin E2 biosynthesis in the murine mammary gland.
J Lipid Res. 2005 Dec;46(12):2636-48.

Chenette EJ, Abo A, Der CJ.
Critical and distinct roles of amino- and carboxyl-terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase.
J Biol Chem. 2005 Apr 8;280(14):13784-92.

Choi J, Ko J, Racz B, Burette A, Lee JR, Kim S, Na M, Lee HW, Kim K, Weinberg RJ, Kim E 
Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases. 
J Neurosci 2005;26:869-79.

Chrzanowska-Wodnicka M, Smyth SS, Schoenwaelder SM, Fischer TH, White GC 2nd.
Rap1b is required for normal platelet function and hemostasis in mice.
J Clin Invest. 2005 Mar;115(3):680-7. Erratum in: J Clin Invest. 2005 Aug;115(8):2296.

Das S, Palmer OP, Leight WD, Surowitz JB, Pickles RJ, Randell SH, Buchman CA.
Cytokine amplification by respiratory syncytial virus infection in human nasal epithelial cells.
Laryngoscope. 2005 May;115(5):764-8.

Ding JD, Burette A, Weinberg RJ 
Expression of soluble guanylyl cyclase in rat cerebral cortex during postnatal development. 
J Comp Neurol 2005;485(3):255-265.

Ehre C, Rossi AH, Abdullah LH, De Pestel K, Hill S, Olsen JC, Davis CW.
Barrier role of actin filaments in regulated mucin secretion from airway goblet cells.
Am J Physiol Cell Physiol. 2005 Jan;288(1):C46-56. Epub 2004 Sep 1.

Flierl A, Chen Y, Coskun PE, Samulski RJ, Wallace DC.
Adeno-associated virus-mediated gene transfer of the heart/muscle adenine nucleotide translocator (ANT) in mouse.
Gene Ther. 2005 Apr;12(7):570-8.

Grieger JC, Samulski RJ.
Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps.
J Virol. 2005 Aug;79(15):9933-44.

Grieger JC, Samulski RJ.
Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps.
J Virol. 2005 Aug;79(15):9933-44.

Hill R, Song Y, Cardiff RD, Van Dyke T.
Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.
Cell. 2005 Dec 16;123(6):1001-11.

Johnson LG.
Applications of imaging techniques to studies of epithelial tight junctions.
Adv Drug Deliv Rev. 2005 Jan 2;57(1):111-21.

Kreda SM, Mall M, Mengos A, Rochelle L, Yankaskas J, Riordan JR, Boucher RC.
Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia.
Mol Biol Cell. 2005 May;16(5):2154-67.

Li, Y., Fanning, A.S., Anderson, J.M. and A. Lavie 
Structure and Mutagenesis of the Occludin Distal C-terminal Cytoplasmic Domain Implicates a Basic Region as the ZO-1 Binding Surface.
J Mol Biol. 2005 Sep 9;352(1):151-64.
Madamanchi NR, Moon SK, Hakim ZS, Clark S, Mehrizi A, Patterson C, Runge MS.
Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms.
Arterioscler Thromb Vasc Biol. 2005 May;25(5):950-6. Epub 2005 Mar 3. 

Matsui H, Verghese MW, Kesimer M, Schwab UE, Randell SH, Sheehan JK, Grubb BR, Boucher RC.
Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces.
J Immunol. 2005 Jul 15;175(2):1090-9.

Melone M, Burette A, Weinberg RJ 
Light microscopic identification and immunocytochemical characterization of glutamatergic synapses in brain
J Comp Neurol 2005;492 (4):495-509

Neuringer IP, Chalermskulrat W, Aris R.
Obliterative bronchiolitis or chronic lung allograft rejection: a basic science review.
J Heart Lung Transplant. 2005 Jan;24(1):3-19.

Neuringer IP, Sloan J, Budd S, Chalermskulrat W, Park RC, Stonebraker JR, O'Neal WK, Aris RM, Randell SH.
Calcineurin inhibitor effects on growth and phenotype of human airway epithelial cells in vitro.
Am J Transplant. 2005 Nov;5(11):2660-70.

Perez-Vilar J, Ribeiro CM, Salmon WC, Mabolo R, Boucher RC.
Mucin granules are in close contact with tubular elements of the endoplasmic reticulum.
J Histochem Cytochem. 2005 Oct;53(10):1305-9

Ribeiro CM, Paradiso AM, Carew MA, Shears SB, Boucher RC.
Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia.
J Biol Chem. 2005 Mar 18;280(11):10202-9.

Perez-Vilar J, Olsen JC, Chua M, Boucher RC.
pH-dependent intraluminal organization of mucin granules in live human mucous/goblet cells.
J Biol Chem. 2005 Apr 29;280(17):16868-81.

Ribeiro CM, Paradiso AM, Schwab U, Perez-Vilar J, Jones L, O'neal W, Boucher RC.
Chronic airway infection/inflammation induces a Ca2+i-dependent hyperinflammatory response in human cystic fibrosis airway epithelia.
J Biol Chem. 2005 May 6;280(18):17798-806

Routt SM, Ryan MM, Tyeryar K, Rizzieri KE, Mousley C, Roumanie O, Brennwald PJ, Bankaitis VA.
Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast.
Traffic. 2005 Dec;6(12):1157-72.

Sims AC, Baric RS, Yount B, Burkett SE, Collins PL, Pickles RJ.
Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs.
J Virol. 2005 Dec;79(24):15511-24.

Stonebraker JR, Wagner D, Lefensty RW, Burns K, Gendler SJ, Bergelson JM, Boucher RC, O'Neal WK, Pickles RJ.
Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection.
J Virol. 2004 Dec;78(24):13755-68.

Tarran R, Button B, Picher M, Paradiso AM, Ribeiro CM, Lazarowski ER, Zhang L, Collins PL, Pickles RJ, Fredberg JJ, Boucher RC.
Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections.
J Biol Chem. 2005 Oct 21;280(42):35751-9.

Thelin WR, Kesimer M, Tarran R, Kreda SM, Grubb BR, Sheehan JK, Stutts MJ, Milgram SL.
The cystic fibrosis transmembrane conductance regulator is regulated by a direct interaction with the protein phosphatase 2A.
J Biol Chem. 2005 Dec 16;280(50):41512-20. Epub 2005 Oct 20.

Tolias KF, Bikoff JB, Burette A, Paradis S, Harrar D, Tavazoie S, Weinberg RJ, Greenberg ME
The Rac1-GEF Tiam1 Couples the NMDA Receptor to the Activity-Dependent Development of Dendritic Arbors and Spines. 
Neuron 2005;45:525-538.

Vincent P, Chua M, Nogue F, Fairbrother A, Mekeel H, Xu Y, Allen N, Bibikova TN, Gilroy S, Bankaitis VA.
A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs.
J Cell Biol. 2005 Feb 28;168(5):801-12.

Xu D, McCarty D, Fernandes A, Fisher M, Samulski RJ, Juliano RL.
Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector.
Mol Ther. 2005 Apr;11(4):523-30.

Zhang L, Bukreyev A, Thompson CI, Watson B, Peeples ME, Collins PL, Pickles RJ.
 Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium.
J Virol. 2005 Jan;79(2):1113-24.

Zucker RM, Lerner JM.
Wavelength and alignment tests for confocal spectral imaging systems.
Microsc Res Tech. 2005 Dec 1;68(5):307-19.

2004  Publications (note this section is currently incomplete)

Ellerbroek SM, Wennerberg K, Arthur WT, Dunty JM, Bowman DR, DeMali KA, Der C, Burridge K.
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.
Mol Biol Cell. 2004 Jul;15(7):3309-19.

Hirsh AJ, Sabater JR, Zamurs A, Smith RT, Paradiso AM, Hopkins S, Abraham WM, Boucher RC.
Evaluation of second generation amiloride analogs as therapy for cystic fibrosis lung disease.
J Pharmacol Exp Ther. 2004 Dec;311(3):929-38.

Kreda, SM; Mall, M; Mengos, A; Jensen, TJ;  Hirtz, S; Seydewitz, HH; Yankaskas, J; Kunzelmann, K; Riordan, JR and Boucher, RC
The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colon
Gastroenterology 2004;126:32-41

Lazarowski E. R., Tarran R., Grubb B. R., van Heusden C., and Boucher
R. C. Nucleotide release provides a mechanism for airway surface liquid homeostasis.
J. Biol. Chem. 2004;279:35551-35556

Lerner JM, Zucker RM.
Calibration and validation of confocal spectral imaging systems.
Cytometry A. 2004 Nov;62(1):8-34. Review.

Mall M, Grubb BR, Harkema JR, O'Neal WK, Boucher RC.
Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice.
Nat Med. 2004 May;10(5):487-93.

McColm JR, Geisen P, Hartnett ME.
VEGF isoforms and their expression after a single episode of hypoxia or repeated fluctuations between hyperoxia and hypoxia: Relevance to clinical ROP.
Mol Vis 2004;10: 512-20

Perez-Vilar J, Randell SH, Boucher RC.
C-Mannosylation of MUC5AC and MUC5B Cys subdomains.
Glycobiology. 2004 Apr;14(4):325-37.


2003  Publications (note this section is currently incomplete)

Ribeiro, C. M. P., Paradiso, A. M., Livraghi, A., and Boucher, R. C. (2003): The mitochondrial barriers segregate agonist-induced calcium-dependent functions in human airway epithelia. J. Gen. Physiol. 122: 377-387.

Schwab, U. E., Ribeiro, C. M. P., and Boucher, R. C. (2003): Role of the Actin Filament Network in Burkholderia multivorans Invasion in Well-Differentiated Human Airway Epithelia. Infect. Immun. 71: 6607-6609.

Coyne, C. B., Ribeiro, C. M. P., Boucher, R. C., and Johnson, L. G. (2003): Acute mechanism of medium chain fatty acid-induced enhancement of airway epithelial permeability. J. Pharm. Experim. Therap. 305: 440-450.

Van Itallie, C.M., Fanning A.S., and Anderson, J.M. (2003) Reversal of Charge Selectivity in Anion or Cation permeable Cell Lines by Expression of Different Claudins.  Am. J. Physiol. Renal Physiol 285(6):F1078-84.

Jaime A. Rivera-Pérez, Jesse Mager and Terry Magnuson, (2003) Dynamic morphogenetic events characterize the mouse visceral endoderm, Developmental Biology 261(2), 470-487.


2002  Publications (note this section is currently incomplete)

Fanning A.S.*, Ma, T.Y., and Anderson, J.M. (2002) Isolation and Functional Characterization of the Actin-Binding Region in the Tight Junction Protein ZO-1.

Schwab, U., Leigh, M., Ribeiro, C., Yankaskas, J., Burns, K., Gilligan, P., Sokol, P., and Boucher, R. (2002):
Patterns of epithelial invasion by different species of the Burkholderia cepacia complex in well-differentiated human airway epithelial cells. Infect. Immun. 70:4547-4555.



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